Summary of derived SRT2104 pharmacokinetic parameters by dose level.
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1Median is presented for tmax.2Geometric mean is presented for AUC0-∞.Abbreviations:Cmax = maximum plasma concentration.tmax = time of peak plasma concentration.AUC0-t = area under the plasma concentration-time curve from zero to the time of the last measurable concentration.AUC0-∞ = area under the plasma concentration-time curve from zero to infinity.t1/2 = half life.CL/F = clearance.
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2015-12-02



