Crystal structure of the Keap1 Kelch domain in complex with the small molecule UCAB#1032 at 1.61 Angstrom resolution

Crystal structure of the Keap1 Kelch domain in complex with the small molecule UCAB#1032 at 1.61 Angstrom resolution Descriptor: (3~{S})-3-[7-[2-(cyclohexylamino)-2-oxidanylidene-ethoxy]naphthalen-2-yl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)propanoic acid, DIMETHYL SULFOXIDE, Kelch-like ECH-associated protein 1, ... Authors: Narayanan, D, Bach, A, Gajhede, M. Deposit date: 2025-01-06 Release date: 2025-09-03 Last modified: 2025-10-08 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Fragment-Based Drug Discovery of Novel High-affinity, Selective, and Anti-inflammatory Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction. Angew.Chem.Int.Ed.Engl., 64, 2025