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Thermolysin inhibition
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创建时间：
2023-09-06
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Small molecule binding data for protein CTP synthase 1 and CTP synthase 2, Uniprot P17812, P70303, P70698, Q5U2N0, and Q9NRF8
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Selectivity of PF1367550.
Calculated IC50 values for PF1367550 against >50 kinases. Data are presented for the kinases that showed >50% inhibition at 1mM ATP or at the Km as indicated (Data from Coe et al., [25]). Selectivity
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A Multi-Kinase Inhibitor Screen Identifies Inhibitors Preserving Stem-Cell-Like Chimeric Antigen Receptor T Cells [RNA-Seq]
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Activity comparison for TBK1 and IKKε.
Number of active compounds (N) detected in each screen for total number detected (unfiltered), number after drug like filtering (filtered.drug-like), hits from the LOPAC and Kinase libraries, and the
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Curve class distribution of small molecules from the kinase inhibitor-enriched library screen.
Curve class distribution of small molecules from the kinase inhibitor-enriched library screen.
Figshare2023-08-04 更新10
