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Ruthenium-Catalyzed Cycloisomerization of 2‑Alkynylanilides: Synthesis of 3‑Substituted Indoles by 1,2-Carbon Migration

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NIAID Data Ecosystem2026-03-10 收录
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We developed ruthenium-catalyzed cycloisomerization of alkynylanilides that gave 3-substituted indoles in high yields. The reaction proceeded via the disubstituted vinylidene ruthenium complex that was formed by the 1,2-carbon migration.

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2017-06-19
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