Metadata record for the manuscript: Dynamic Contrast-Enhanced Breast MRI Features Correlate with Invasive Breast Cancer Angiogenesis
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<b>Summary</b> This metadata record provides details of the data supporting the claims of the related manuscript: “Dynamic Contrast-Enhanced Breast MRI Features Correlate with Invasive Breast Cancer Angiogenesis”. The related study evaluated the association of semi-quantitative kinetic and radiomic breast cancer features on dynamic contrast enhanced (DCE)-MRI with microvessel density (MVD), a marker for angiogenesis, as angiogenesis is a critical component of breast cancer development, and identification of imaging-based angiogenesis assays has prognostic and treatment implications. Type of data: dynamic contrast enhanced magnetic resonance imaging (DCE-MRI), tabular metadata Subject of data: <i>Homo sapiens, </i>microvessel density (MVD)<i></i> Sample size: 27 Recruitment: Patients over the age of 18 were prospectively recruited for the study if they had a new diagnosis of stage I - III invasive breast cancer with a minimum lesion size of 1.5 cm identified on core needle biopsy and underwent a clinical breast MRI at SCCA to evaluate the extent of disease. <b>Data access</b> The de-identified DCE-MRI data, measures and metadata are shared openly in the file 'Xiao_MVD_Data_npjBreastCancer_repository.xlsx', which is attached with this data record.The pathology CD-31 stained slides data are not publicly available for the following reason: no digitised versions of the slides have been created. <b>Corresponding author(s) for this study</b> Savannah C. Partridge, PhD, Department of Radiology, University of Washington, Seattle, WA. Email: scp3@u.washington.edu <br> <b>Study approval </b> This prospective study was approved by the Institutional Review Board of the Fred Hutchinson Cancer Research Center (IR#8148) and was compliant with the Health Insurance Portability and Accountability Act. All patients provided informed consent and were enrolled at the University of Washington/Seattle Cancer Care Alliance (SCCA) between January 2016 and July 2017.
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figshare
创建时间:
2021-04-13



