Supplementary Data from KIF15-Mediated Stabilization of AR and AR-V7 Contributes to Enzalutamide Resistance in Prostate Cancer

NIAID Data Ecosystem2026-04-29 收录

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https://figshare.com/articles/dataset/Supplementary_Data_from_KIF15-Mediated_Stabilization_of_AR_and_AR-V7_Contributes_to_Enzalutamide_Resistance_in_Prostate_Cancer/22427620 数据链接链接失效反馈

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Supplementary Tables

创建时间：

2021-02-15

Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (Affymetrix). Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (Affymetrix)

耐药性前列腺癌

激素受体靶向治疗

Constitutively active androgen receptor (AR) signaling confers resistance to AR-targeted therapies. Here we show that the ubiquitin-mediated proteolysis pathway plays a critical role in the degradatio

NIAID Data Ecosystem50

Identification of Selective SWI/SNF Dependencies in Enzalutamide-Resistant Prostate Cancer

耐药性前列腺癌

表观遗传调控

Enzalutamide (ENZA) is a potent second-generation antiandrogen commonly used to treat hormone-sensitive and castration-resistant prostate cancer (CRPC) patients. While initially effective, the respons

NIAID Data Ecosystem10

Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.. Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.

乳腺癌分子机制

受体信号通路

Inhibitory crosstalk between estrogen receptor alpha (ER alpha ) and aryl hydrocarbon receptor (AHR) regulates 17-estradiol (E2)-dependent breast cancer cell signaling. ER alpha and AHR are transcript

NIAID Data Ecosystem10

Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation. Homo sapiens

RNA稳定性调控

受体信号通路

Roquin2, and its paralog Roquin1, are key regulator of mRNA decay. Roquin proteins recognize mRNAs containing a 3’-UTR stem-loop motif, called constitutive decay element (CDE), through the ROQ domain.

NIAID Data Ecosystem20

DataSheet_1_Paired Rheumatoid Arthritis Synovial Biopsies From Small and Large Joints Show Similar Global Transcriptomic Patterns With Enrichment of Private Specificity TCRB and TCR Signaling Pathways.pdf

类风湿关节炎滑膜病理

受体信号通路

ObjectivesWe explored histological and transcriptomic profiles of paired synovial biopsies from rheumatoid arthritis (RA) patients, in order to assess homogeneity in synovial tissue at the individual

NIAID Data Ecosystem10

Supplementary Data from KIF15-Mediated Stabilization of AR and AR-V7 Contributes to Enzalutamide Resistance in Prostate Cancer

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