Trifluoromethyl ketones (TFMKs) readily form stable hydrates and hemiketals in solution, allowing them to interact with biomolecules as hydrogen-bond donors. This interaction is governed by both the h
Guest–host hydrogen bonding strongly affects the physical properties of clathrate hydrate, such as the thermodynamic stability, water dynamics, and dielectric properties, but attempts to quantify the
Text file with 454 measured values of pK BHX (see J Med Chem 2009 52:4073-4086) that was published as supplementary information for JCAMD 2017 31:163-181. This supersedes the corresponding f
A tripodal ligand based on 2-hydroxypyridine is presented. Cu–Cl adducts of H3thpa with CuI and CuII provide complexes featuring highly directed, intramolecular hydrogen-bonding interactions. An upper
Weak hydrogen bonding in uracil and 4-cyano-4‘-ethynylbiphenyl, for which single-crystal diffraction structures reveal close CH···OC and C⋮CH···N⋮C distances, is investigated in a study that combines