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Crystal structure of Schistosoma mansoni HDAC8 mutant H292M complexed with PCI-34051

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal structure of Schistosoma mansoni HDAC8 mutant H292M complexed with PCI-34051 Descriptor: 1-[(4-methoxyphenyl)methyl]-~{N}-oxidanyl-indole-6-carboxamide, DIMETHYLFORMAMIDE, GLYCEROL, ... Authors: Shaik, T.B, Marek, M, Romier, C. Deposit date: 2018-10-01 Release date: 2018-10-31 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.899 Å) Cite: Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018

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2018-10-01
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