Longitudinal Multi'omics of the Human Microbiome in Inflammatory Bowel Disease

The main Inflammatory Bowel Disease (IBD) Multi'omics Database (IBDMDB) study includes multi'omics measurements from over 100 subjects, sampled biweekly over up to a year in both adult and pediatric patients with IBD (Crohn's disease and ulcerative colitis), along with non-IBD controls. Data types include fecal metagenomes, metatranscriptomes, metabolomes, and proteomes, as well as host genetics, intestinal biopsy transcriptomes, epigenetics, and 16S amplicon profiles. Subjects' medical histories and demographics are collected at baseline and medication, diet, and disease activity profiled longitudinally.