Additional Data

Here, we provide: Robjects pertaining to scRNA-seq (Seurat) and snATAC-seq (Signac) analysis. These contain the single-cell and single-nuclei used in downstream analyses. Tables containing information about the gene markers identified for each cluster in scRNA-seq, peak markers identified for each cluster in snATAC-seq, and motif enrichment analyses using chromVAR motif scores. Differential gene expression and motif enrichment analyses was performed using Wilcoxon rank sum test comparing the distribution of gene expression or chromVAR motif scores between cells in the cluster and all other cells. Differential peak analyses was performed using FindAllMarkers in Signac.