Sexual dimorphism of early transcriptional reprogramming in degenerating peripheral nerves

Transcriptional changes are distinct in female and male mice in the time course of peripheral nerve injury response. Here, we present sexually dimorphic transcriptome profiles established in the space of 24 h period after sciatic nerve axotomy. Overall design: Compare transcriptomes of female and male mice after sciatic nerve axotomy to identify sexually dimorphic molecular signatures, upstream regulators and signaling pathways.