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Crystal structure of human carbonic anhydrase I in complex with the 1-(2-hydroxy-5-sulfamoylphenyl)-3-(2-methoxyphenyl)urea inhibitor

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of human carbonic anhydrase I in complex with the 1-(2-hydroxy-5-sulfamoylphenyl)-3-(2-methoxyphenyl)urea inhibitor Descriptor: 1-(2-methoxyphenyl)-3-(2-oxidanyl-5-sulfamoyl-phenyl)urea, Carbonic anhydrase 1, GLYCEROL, ... Authors: Ferraroni, M, Supuran, C.T, Bozdag, M, Chiapponi, D. Deposit date: 2017-12-15 Release date: 2018-10-10 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX. J.Med.Chem., 61, 2018

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2017-12-15
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