Crystal structure of human MBP-Myeloid cell leukemia 1 (Mcl-1) in complex with BRD810 inhibitor
收藏Protein Data Bank Japan2024-11-06 更新2026-04-19 收录
下载链接：
https://pdbj.org/mine/summary/8t6f
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of human MBP-Myeloid cell leukemia 1 (Mcl-1) in complex with BRD810 inhibitor Descriptor: (3aM,9S,15R)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-yl)oxy]propyl}-2-methyl-15-[2-(morpholin-4-yl)ethyl]-2,10,11,12,13,15-hexahydropyrazolo[4',3':9,10][1,6]oxazacycloundecino[8,7,6-hi]indole-8-carboxylic acid, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... Authors: Poncet-Montange, G, Lemke, C.T. Deposit date: 2023-06-15 Release date: 2024-06-19 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models. Nat Cancer, 5, 2024
创建时间：
2023-06-15
