Expression data from KYSE-150-shCtrl and KYSE-150-shCDKL3 cells

ESCC tumor tissues possessed a significantly higher expression of CDKL3 than matched adjacent normal tissues. CDKL3 acts as a new oncogene in ESCC cell line TE-1. However, the molecular mechanisms and biological effects of CDKL3 in esophageal squamous cell carcinoma (ESCC) remain unknown. We used microarrays to elucidate the molecular mechanisms through which CDKL3 promotes the proliferation of ESCC cancer cells. KYSE-150 cells at the logarithmic growth phase were transfected with the recombinant lentiviral vector (LV) named as KD (KYSE-150-shCDKL3 cells) labeled with green fluorescent or NC(KYSE-150-shCtrl) labeled with green fluorescent. We analyzed the gene expression profiles of 3 pairs of KYSE-150-shCtrl and KYSE-150-shCDKL3 cells by GeneChip® PrimeView™ Human Gene Expression Array.