HIV-1 Protease WT (NL4-3) in Complex with a Darunavir Derivative
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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HIV-1 Protease WT (NL4-3) in Complex with a Darunavir Derivative Descriptor: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(1,3-benzothiazol-6-yl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, Protease, SULFATE ION Authors: Lockbaum, G.J, Rusere, L.N, Henes, M, Kosovrasti, K, Lee, S.K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. Deposit date: 2021-01-14 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.952 Å) Cite: HIV-1 Protease Inhibitors with a P1 Phosphonate Modification Maintain Potency against Drug Resistant Variants by Increased van der Waals Contacts with Flaps Residues To Be Published
创建时间:
2021-01-14



