首页/数据集/Dissecting the dynamic changes of 5-hydroxymethylcytosine in T cell development and differentiation

Dissecting the dynamic changes of 5-hydroxymethylcytosine in T cell development and differentiation

ChEBI2014-08-04 更新2026-07-21 收录

表观遗传修饰

T细胞免疫学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-59213 数据链接链接失效反馈

官方服务：

资源简介：

Dissecting the dynamic changes of 5-hydroxymethylcytosine in T cell development and differentiation

应用场景：

创建时间：

2014-08-04

DNA复合物

表观遗传修饰

Crystal structure of the TAL effector dHax3 bound to methylated dsDNA Descriptor: DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*TP*AP*GP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*(5CM)P*TP*AP*(5CM)P

Protein Data Bank Japan2023-11-08 更新40

SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2

细胞氧化还原调控

表观遗传修饰

We investigated the effect of SIRT6-knockout on gene expression and H3K4me3 modification profile in human mesenchymal stem cells. Overall design: RNAs isolated from SIRT6+/+ and SIRT6-/- hMSCs at earl

NIAID Data Ecosystem40

Transcriptomic profiling of naïve and memory phenotype CD8 T cells in Dock2-deficient mice. Transcriptomic profiling of naïve and memory phenotype CD8 T cells in Dock2-deficient mice

T细胞免疫学

转录组学分析

Transcriptomic data linked to our study showing that DOCK2 sets the threshold for entry into the virtual memory CD8+ T cell compartment by negatively regulating tonic TCR triggering Overall design: RN

NIAID Data Ecosystem10

GO:0070989 (oxidative demethylation)

表观遗传修饰

功能基因网络

This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.

NIAID Data Ecosystem40

RVD HA specifically contacts 5mC through van der Waals interactions

DNA相互作用

表观遗传修饰

RVD HA specifically contacts 5mC through van der Waals interactions

NIAID Data Ecosystem20