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DNA methylation status of myelinating Schwann cells during development and in diabetic neuropathy

ChEBI2014-01-27 更新2026-07-21 收录

周围神经表观遗传学

神经病变机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-45702 数据链接链接失效反馈

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DNA methylation status of myelinating Schwann cells during development and in diabetic neuropathy

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2014-01-27

细胞DNA甲基化

神经病变机制

DNA methylation is a key epigenetic regulator of mammalian embryogenesis and somatic cell differentiation. Using high-resolution genome-scale maps of methylation patterns, we show that the formation o

NIAID Data Ecosystem60

Human myelin protein P2, mutant T51P

蛋白质结构解析

神经病变机制

Human myelin protein P2, mutant T51P Descriptor: D-MALATE, Myelin P2 protein, PALMITIC ACID, ... Authors: Ruskamo, S, Kursula, P. Deposit date: 2017-02-11 Release date: 2017-08-09 Last modified: 2024-

Protein Data Bank Japan2024-01-17 更新50

Rosiglitazone Treatment Reduces Diabetic Neuropathy in STZ treated DBA/2J mice

神经病变机制

药物靶点发现

Diabetic Neuropathy (DN) is a common complication of diabetes. Currently, there is no drug treatment to prevent or slow the development of DN. Rosiglitazone (Rosi) is a potent insulin sensitizer and

NIAID Data Ecosystem40

MicroRNA expression profile of human umbilical vein endothelial cells in response to Coxsackievirus A10 infection

病毒miRNA表达

神经病变机制

Coxsackievirus A10 (CV-A10) constitutes one of the major pathogens of hand, foot, and mouth disease (HFMD), which can cause mild to severe illness and even death. Most of these severe and death cases

NIAID Data Ecosystem50

HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins

神经病变机制

施万细胞-轴突相互作用

The pathogenesis of peripheral neuropathies in adults is linked to maintenance mechanisms that are not well understood. Here, we elucidate a novel critical maintenance mechanism for Schwann cell (SC)–

Figshare2016-01-15 更新40

DNA methylation status of myelinating Schwann cells during development and in diabetic neuropathy

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