Results of association analyses for 41 single nucleotide polymorphisms (SNPs) analysed.
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Odds ratios (OR) with 95% confidence intervals (CI) for the minor alleles of these SNPs for children with T1D with two different phenotypes of clustered autoimmunity are shown. Children with multiple autoimmune diseases were compared to those with T1D only (n = 1,685) and children from autoimmune families to children without any additional autoimmune diseases in the family (n = 824). Autoimmune families: ≥4 diagnoses of autoimmune diseases (T1D or other) and/or ≥3 different autoimmune diseases (T1D or other) in first- and/or second-degree relatives and/or the index child. (CHR = chromosome, MAF = minor allele frequency, FDR P value = false discovery rate corrected P value).
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2017-11-29



