Cryo-EM structure of CDK7 subunit of CAK in complex with inhibitor LDC4297
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Cryo-EM structure of CDK7 subunit of CAK in complex with inhibitor LDC4297 Descriptor: 2-[(3S)-piperidin-3-yl]oxy-8-propan-2-yl-N-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine, CDK-activating kinase assembly factor MAT1, Cyclin-dependent kinase 7 Authors: Cushing, V.I, Koh, A.F, Feng, J, Jurgaityte, K, Bahl, A.K, Ali, S, Kotecha, A, Greber, B.J. Deposit date: 2023-05-30 Release date: 2024-03-20 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (2.1 Å) Cite: High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design. Nat Commun, 15, 2024
创建时间：
2023-05-30
