Comparative mosaic trend analysis of coronavirus structural proteins (S, E, M, N) using domain-resolved alignments.

Structural Protein Mosaic Analysis: Sarbecovirus vs. Merbecovirus - Reference sequences: NCBI RefSeq (YP_* accessions) - Domain annotation: HMMER v3.3.2 against Pfam-A - Alignment: MAFFT L-INS-i - Metrics: Shannon entropy, percent identity, gap fraction, hydrophobicity variance (Kyte-Doolittle) Study by: Tahir Bhatti ([e-mail])