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Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2

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Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3fj6
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Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2 Descriptor: (2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide, ACETATE ION, Dihydroorotate dehydrogenase, ... Authors: Heikkila, T. Deposit date: 2008-12-14 Release date: 2009-06-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases J.Med.Chem., 52, 2009
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2008-12-14
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