Tubulin-RB3_SLD in complex with compound 12e

Tubulin-RB3_SLD in complex with compound 12e Descriptor: 7-methoxy-4-[2-(morpholin-4-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: White, S.W, Yun, M. Deposit date: 2022-02-01 Release date: 2023-04-12 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. Acs Pharmacol Transl Sci, 6, 2023