官方服务:
资源简介:
Mouse CNS immune cell RNA transcriptome
应用场景:
创建时间:
2017-09-17
相关数据集
A study of how homozygous ALS-linked FUS P525L mutations perturb transcriptome profile in human iPSC-derived microglia
Purpose: The FUS P525L mutation is highly penetrant and causes ALS cases with earlier disease onset and more aggressive progression. This study aims to understand the impact of P525L mutations in mic
NIAID Data Ecosystem40
The major risk factors for Alzheimer's disease: Age, Sex and Genes, modulate the microglia response to AÃ plaques (KW)
Microglia are involved in Alzheimer's disease (AD) by adopting activated phenotypes. How ageing in the absence or presence of Ã-amyloid (AÃ) deposition in different brain areas affects this response
NIAID Data Ecosystem10
KOLF2.1J iTF-Microglia: A standardized platform to study microglial transcriptional regulatory networks in CNS disease [Hi-C]
Understanding transcriptional regulatory networks (TRNs) in microglia is key to uncovering mechanisms driving central nervous system (CNS) disorders. Human iPSC-derived models offer a tractable system
NIAID Data Ecosystem00
RNA sequencing data of microglia isolated from brains of WT, Hexb-tdTomato, Hexb-CreERT2 and Hexb-KO mice.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
NIAID Data Ecosystem30
E-GEOD-43366
Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
NIAID Data Ecosystem00



