Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-II-153
收藏Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
下载链接：
https://pdbj.org/mine/summary/7mr9
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-II-153 Descriptor: 1,2-ETHANEDIOL, 2-methyl-4-[3-(2-oxopyrrolidin-1-yl)phenyl]isoquinolin-1(2H)-one, Bromodomain-containing protein 4 Authors: Chan, A, Schonbrunn, E. Deposit date: 2021-05-07 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
创建时间：
2021-05-07
