Kassiopeia

Kassiopeia is a web application for the generation, storage, and presentation of genome-wide analyses of mutually exclusive exonomes. In the prediction pipeline relaxed parameters were used to also identify very divergent exons at the expense of potentially incorporating false positive predictions. However, Kassiopeia provides many filters to adjust these parameters to narrow the results further down at the analysis level. Kassiopeia also offers several search options so that users can analyse the data from the whole genome scale to the single gene case. In order to provide test data we predicted the mutually exclusive exonomes of twelve sequenced Drosophila species, of the plant Arabidopsis thaliana, of the flatworm Caenorhabditis elegans, and of human.