官方服务:
资源简介:
Differentially expressed genes across microglia expressing different APOE isoforms and the APOE knockout.
应用场景:
创建时间:
2024-05-06
相关数据集
Distinct amyloid-b and tau associated microglia profiles in Alzheimer's disease
Alzheimer's disease (AD) is the most prevalent form of dementia and is characterized by abnormal extracellular aggregates of amyloid-b and intraneuronal hyperphosphorylated, tau tangles and neuropil t
NIAID Data Ecosystem110
Unique microglia expression profile in developing white matter.
Recently we demonstrated that amoeboid microglia in white matter regions are essential for proper oligodendrocyte homeostasis and myelinogenesis in the first postnatal week of mice. Amoeboid microglia
NIAID Data Ecosystem20
Droplet-based scRNA-seq of plasma-positive microglia and plasma-negative microglia from hypothalamus region in young mice
Microglia are highly responsive to their local environment and signals from the periphery. Blood plasma proteins readily permeate the healthy brain parenchyma. However, whether microglia are responsiv
NIAID Data Ecosystem10
Transcriptome sequencing elucidates gene modules in microglia. Transcriptome sequencing elucidates gene modules in microglia
Microglia are multifunctional cells that are important for brain development and homeostasis. Despite the growing evidence of their complexity, the field lacks a unified system for categorizing the ma
NIAID Data Ecosystem20
Transcriptome profiles of wild-type, IRF8KO, IRF8cKO, Batf3KO, 5xFAD, and 5xFAD/IRF8KO microglia [RNA-seq]
The role of the lineage-determining transcription factor IRF8 in microglia remains unelucidated. We report the genome-wide, transcriptome profiles of wild-type, IRF8KO, IRF8cKO, Batf3KO, 5xFAD, and 5x
NIAID Data Ecosystem10



