Human 11beta-Hydroxysteroid Dehydrogenase Type 1 in complex with AZD8329
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https://pdbj.org/mine/summary/4p38
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Human 11beta-Hydroxysteroid Dehydrogenase Type 1 in complex with AZD8329 Descriptor: 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid, CHLORIDE ION, Corticosteroid 11-beta-dehydrogenase isozyme 1, ... Authors: Ogg, D, Hargreaves, D, Gerhardt, S. Deposit date: 2014-03-06 Release date: 2014-04-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Novel acidic 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329). J.Med.Chem., 55, 2012
创建时间：
2014-03-06
