Human GAR transformylase in complex with GAR substrate and AGF305 inhibitor

Human GAR transformylase in complex with GAR substrate and AGF305 inhibitor Descriptor: GLYCINAMIDE RIBONUCLEOTIDE, N-{5-[4-(2-amino-4-oxo-1,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl]-3-fluoropyridine-2-carbonyl}-L-glutamic acid, Phosphoribosylglycinamide formyltransferase Authors: Wong-Roushar, J, Dann III, C.E. Deposit date: 2022-12-05 Release date: 2023-05-10 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Multitargeted 6-Substituted Thieno[2,3- d ]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism. Acs Pharmacol Transl Sci, 6, 2023