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REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease. REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease

NIAID Data Ecosystem2026-03-10 收录

阿尔茨海默病基因表达调控

iPSC疾病模型

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA482597 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2018-07-24

ALS疾病分子机制

iPSC疾病模型

We established iPSCs from healthy donors, FUS-ALS and SOD1-ALS patients. Using our differentiation protocol originally developed by Reinhardt et al.,2013, we diferentiated these iPSCs toward spinal mo

NIAID Data Ecosystem70

Additional file 5 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis

阿尔茨海默病蛋白质组学

iPSC疾病模型

Additional file 5: Table S4. Common and dysregulated proteins across models.

Figshare2024-08-16 更新40

Additional file 2 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis

阿尔茨海默病蛋白质组学

iPSC疾病模型

Additional file 2: Table S1. Global proteome analysis for ADHG.

Figshare2024-08-16 更新30

File S1 - The Disease-Specific Phenotype in Cardiomyocytes Derived from Induced Pluripotent Stem Cells of Two Long QT Syndrome Type 3 Patients

iPSC疾病模型

心脏电生理学

The following files are included in File S1: Figure S1, Schematic of voltage-gated sodium channel structure and location of mutations described in this study. Figure S2, ECG analysis of the two LQTS-

NIAID Data Ecosystem60

Human iPSC-based disease modeling studies identify a common mechanistic defect and potential therapies for AMD and related macular dystrophies.

黄斑变性机制研究

iPSC疾病模型

Raw uncropped western blot and gelatin zymography gel images from Main and Supplementary Figures

Mendeley Data30