Deep sequencing of endogenous mRNA from Caenorhabditis elegans in the presence of 2-deoxy-D-glucose (DOG) at 4 different time points
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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Background: C. elegans fed with a chemical inhibitor of glucose, namely 2-deoxy-D-glucose (DOG), exhibit considerably extended life span. DOG, in contradiction to D-glucose, cannot be metabolized in the glycolytic pathway. This results in the fact that less glucose is available for ATP production, and thus makes DOG-feeding of the roundworms equivalent to glucose restriction.The RNA-seq data comprises 4 age groups (1, 5, 10 and 20 days after L4)Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de)
提供机构：
Leibniz Institute for Age Research - Fritz Lipmann Institute
创建时间：
2022-02-20
