The novel p300/CBP inhibitor A-485 uncovers a unique mechanism of action to target AR in castrate resistant prostate cancer
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/5kj2
下载链接
链接失效反馈官方服务：
资源简介：
The novel p300/CBP inhibitor A-485 uncovers a unique mechanism of action to target AR in castrate resistant prostate cancer Descriptor: Histone acetyltransferase p300, N-[(4-fluorophenyl)methyl]-2-{(1R)-5-[(methylcarbamoyl)amino]-2',4'-dioxo-2,3-dihydro-3'H-spiro[indene-1,5'-[1,3]oxazolidin]-3'-yl}-N-[(2S)-1,1,1-trifluoropropan-2-yl]acetamide, SODIUM ION Authors: Jakob, C.G, Qiu, W, Edalji, R.P, Sun, C. Deposit date: 2016-06-17 Release date: 2017-09-27 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature, 550, 2017
创建时间：
2016-06-17
