Silver-Assisted [3 + 2] Annulation of Nitrones with Isocyanides: Synthesis of 2,3,4-Trisubstituted 1,2,4-Oxadiazolidin-5-ones
收藏NIAID Data Ecosystem2026-03-11 收录
下载链接：
https://figshare.com/articles/dataset/Silver-Assisted_3_2_Annulation_of_Nitrones_with_Isocyanides_Synthesis_of_2_3_4-Trisubstituted_1_2_4-Oxadiazolidin-5-ones/11878161
下载链接
链接失效反馈官方服务：
资源简介：
A silver-assisted method for [3 +
2] annulation of nitrones with
isocyanides has been developed. The developed protocol allows access
to a variety of 2,3,4-trisubstituted 1,2,4-oxadiazolidin-5-one derivatives
as single diastereomers in good to excellent yields using silver oxide
as the catalyst and molecular oxygen as the terminal oxidant. A plausible
mechanism involving a nucleophilic addition/cyclization/protodeargentation/oxidation
pathway is proposed on the basis of experimental results.
创建时间：
2020-02-04
