Cap analysis gene analysis (CAGE) of Ba/F3 cells harbouring FLT3-ITD mutations (mouse)
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https://www.ncbi.nlm.nih.gov/sra/SRP260263
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The purpose of the experiment is to investigate transcriptome signatures of FLT3-ITD and TKD double mutations in AML and the underlying molecular mechanism of mutation-driven acquired resistance. We identify 1945 upregulated and 1470 downregulated promoters in FLT3-ITD/D835 mutant Ba/F4 cells compared to cells with FLT3-ITD (FDR<0.05). Overall design: Examination of differentially expressed promoters beween FLT3-ITD Ba/F3 cells expressing FLT3-ITD and Ba/F3 cells expressing FLT3-ITD/D835
创建时间:
2023-05-16



