Multifunctional Poly(2-Oxazoline) Based Nanoparticles for Microglia-Targeting Therapeutics

Therapeutic options for treating inflammation in brain diseases currently remain limited owing to the current available drugs are not fully efficient. This may because the drug can be easily cleared to the secretion system and also brain itself considered complex. One of the strategies to overcome this issue is by utilizing the new material carrier for the drug to ensure them delivered to the target diseases. Here, this thesis examines how the new material can bring the current anti-inflammatory drug to the target brain cells more precisely and reduce inflammation, with fewer side-effects.