Supplementary materials for the manuscript "Association of HLA-class II alleles with risk of relapse in myeloperoxidase-antineutrophil cytoplasmic antibody positive vasculitis in the Japanese population"

Supplementary Table S1. Association analysis of each <em>HLA-DRB1</em> allele with occurrence of relapse and time to relapse. <br> Supplementary Table S2. Association analysis of each <em>HLA-DQA1</em> allele with occurrence of relapse and time to relapse. <br> Supplementary Table S3. Association analysis of each <em>HLA-DQB1</em> allele with occurrence of relapse and time to relapse. <br> Supplementary Table S4. Association analysis of each <em>HLA-DPB1</em> allele with occurrence of relapse and time to relapse. Supplementary Table S5 Association analyses of HLA-DRβ1_13S encoding alleles with susceptibility and relapse-free survival. Supplementary Figure S1. Sanger sequencing chromatograms around the <em>HLA-DQA1*03:02</em> tagSNP rs11545686. Representative Sanger sequencing chromatograms corresponding to each of the three genotypes are shown. The rs11545686C allele tags <em>HLA-DQA1*03:02.</em> <em>HLA-DQA1 </em>genotype of each subject determined by PCR-SSOP was <em>DQA1*03:02/03*02</em> (relapse ID 36), <em>DQA1*03:02/05:07 (</em>relapse ID 156) and <em>DQA1*</em> <em>01:01/01:02</em> (relapse ID 164), as shown in Supplementary Data 1. <br> Supplementary Data 1. Clinical information and HLA genotypes in each subject examined for susceptibility and relapse. <br> Susceptibility Data 2. Association of each HLA -class II amino acid with relapse-free survival. <br>