Gut microbiota development in allergic disease: A prospective study from infancy to school-age

Compositional changes of the gut microbiota have been implicated in IgE-associated allergic disease but there is lack of longitudinal studies. We examined gut microbiota development from infancy to school age in relation to onset of IgE-associated allergic diseases. At 8 years of age, we also examined the relationship between gut microbiota and T cell regulation, estimated as responses to polyclonal T-cell activation.