Saccharomyces cerevisiae S288c Genome sequencing. Saccharomyces cerevisiae S288c
收藏NIAID Data Ecosystem2026-03-09 收录
官方服务：
资源简介：
To determine genome-wide association of Mediator and RNA Polymerase II in wild type and mutant yeast
应用场景：
创建时间：
2014-09-26
相关数据集
Ssu72 and Ser5P-RNAPII ChIPseq in hESCs. GROseq analysis in siCtrl and siSSu72 transfected hESCs.. Homo sapiens
Ssu72 is a Ser5P-RNAPII phosphatase, nevertheless few targets have been characterized and its role in mammal cells remains elusive. Using ChIPseq and GROseq technologies we aimed to identify Ssu72 tar
NIAID Data Ecosystem40
Synergistic anti-tumor effect of combining selective CDK7 and BRD4 inhibition in MYCN-amplified neuroblastoma
Cyclin-dependent kinases (CDKs) that have critical roles in RNA polymerase II (Pol II)-mediated gene transcription are emerging as therapeutic targets in cancer. We have previously shown that THZ1, a
NIAID Data Ecosystem20
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors [Affymetrix]. Homo sapiens
Cyclin-dependent kinases 12 and 13 (CDK12 and CDK13) play critical roles in the regulation of gene transcription. However, the absence of CDK12 and CDK13 inhibitors has hindered the ability to investi
NIAID Data Ecosystem20
Homo sapiens epigenomics. Homo sapiens strain:Hela cells
genomic DNA and mRNA from Hela cells To analyzed transcriptional regulation in Hela cells, we performed RNASeq and ChIPSeq using monoclonal antibodies which react Ser2P or Ser5P of RNAP2 specifically.
NIAID Data Ecosystem20
Promoter-specific changes in initiation, elongation and homeostasis of histone H3 acetylation during CBP/p300 Inhibition [GRO-Seq]. Promoter-specific changes in initiation, elongation and homeostasis of histone H3 acetylation during CBP/p300 Inhibition [GRO-Seq]
Regulation of RNA Polymerase II (Pol2) elongation in the promoter proximal region is an important and ubiquitous control point for gene expression in metazoans. We report that transcription of the ade
NIAID Data Ecosystem20
