HEMATOPOIETIC STEM CELL TRANSPLANTATION DISRUPTS AGE-RELATED GUT MICROBIOTA SIGNATURES IN PEDIATRIC AND ADULT RECIPIENTS

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) profoundly reshapes the gut microbiome (GM), yet age-related differences in this process remain incompletely understood. In this study, we analyzed stool samples from a cohort of pediatric and adult patients collected before allo-HSCT and at neutrophil engraftment to assess GM dynamics.