Hydrazonyl Radical-Participated Tandem Reaction: A Strategy for the Synthesis of Pyrazoline-Functionalized Oxindoles
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https://figshare.com/articles/dataset/Hydrazonyl_Radical_Participated_Tandem_Reaction_A_Strategy_for_the_Synthesis_of_Pyrazoline_Functionalized_Oxindoles/2097625
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资源简介:
An
efficient and practical tandem cyclization/addition/cyclization
strategy is developed for the initial generated hydrazonyl radicals
derived from the oxidation of β,γ-unsaturated hydrazones.
By using this protocol, structurally novel pyrazoline-functionalized
oxindoles are prepared by the reaction of easily accessible β,γ-unsaturated
hydrazones with N-aryl acrylamides under the metal-
and solvent-free conditions of DTBP (di-tert-butyl
peroxide) via a tandem intra/intermolecular C–N/C–C/C–C
bond formation.
创建时间:
2016-02-12



