Genome-wide structure and organization of eukaryotic pre-initiation complexes

Rhee et al. applied a high-resolution sequencing ChIP-based method called ChIP-exo to profile the structural and positional organization of transcription pre-initiation complexes (RNA polymerase II, protein complexes TFIIA, TFIIB, TFIID (or TBP), TFIIE, TFIIF, TFIIH and TFIIK) across the budding yeast genome