Supplemental Material for Zhou et al., 2020

<i>Salmonella</i> <i>enterica</i> serovar Rissen (<i>S.</i> Rissen) is a widely distributed serotype; however, its virulence and pathogenicity are poorly understood. In this study, the pathogenicity and antibiotic resistance of a representative <i>S</i>. Rissen isolate was investigated. The cell model showed that <i>S.</i> Rissen preferred to replicate in human macrophage cells U937 compared to murine macrophage cells RAW264.7, suggesting that it has a level of host adaptability. Genome sequencing and comparison analysis revealed that the distribution and nonsynonymous single nucleotide polymorphisms of virulence factors in <i>S.</i> Rissen were similar to those in<i> S</i>. Typhi rather than to those in <i>S.</i> Typhimurium.