Datasets: Natural killer cells associate with malignant epithelial cells in the pancreatic ductal adenocarcinoma tumor microenvironment

The following are necessary data files for the manuscript "Natural killer cells associate with malignant epithelial cells in the pancreatic ductal adenocarcinoma tumor microenvironment":

.zip files for TMA_1, TMA_2, TMA_3, and TMA_4 are .mcd files acquired from imaging mass cytometry (IMC) for each slide of the pancreas TMA slide series

pancreas_TMA_sample_info.xlxs includes info on all samples of the TMA slide series that were imaged by IMC

custom_gates_0.zip includes histoCAT-derived single cell data files from all IMC samples in the pancreas TMA to be used for single cell analyses in R

PDAC_IMC.RDS is a Seurat object of the IMC-derived PDAC single cell data to use for single cell and spatial analyses

PDAC_sce is a SingleCellExperiment object of IMC-derived PDAC single cell data to use for spatial analyses

mat.RDS is a distance matrix of PDAC cell types to use in R to generate network graph (Figure 2)