Morphological heart age from CTA: Predictions, Performance and Saliency Maps

This data distribution contains regression results for age prediction from computed tomography angiography images from the SCAPIS dataset, as well as proof-of-concept experiments concerning the prediction of known volumetric features estimated through segmentation of the images.

Each sub-folder represents one experiment.

For each experiment (sex-stratified), there is a csv file '0.csv'with the following structure

Row 1: subject id1, subject id2, subject id3, ...Row 2: reference value1, reference value2, reference value3, ...Row 3: predicted value1, predicted value2, predicted value3, ...

There is also a file 'results_summary.txt' which provides a text output of the quality measures corresponding to each experiment:Mean Absolute Error (MAE)R^2 (R2)Pearson correlation (r_p)Spearman correlation (r_s)Intraclass Correlation Coefficient (ICC)

The following sub-folders/experiments contain saliency maps:- main (the main experiment with PCA from the whole heart)- main_linear (the main experiment without PCA from the whole heart)- poc_lvv (proof-of-concept: left ventricle volume)- poc_rvv (proof-of-concept: right ventricle volume)- poc_lav (proof-of-concept: left atrium volume)- poc_rav (proof-of-concept: right atrium volume)- poc_myov (proof-of-concept: myocardium volume)- poc_av (proof-of-concept: aorta volume)

The feature subsets use the following encoding (for the feature subset experiments, the path contains the numbers representing the included features):1: Median Density2: Median Volume3: Stddev Density4: Stddev Volume

Ethics:The subjects/images are all anonymized, with a chronological age rounded to whole months.

Ethics approval was obtained from the Swedish Ethical Review Authority (Dnr 2022-07308-01) to conduct this research study related to human subjects, with associated sex and age information. All subjects provided informed written consent for their collected data to be used for research and for that research to be published. The study adheres to the Declaration of Helsinki. SCAPIS has been approved as a multicentre trial by the ethics committee at Umea University and adheres to the Declaration of Helsinki.