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Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with N-METHYL-FHBT

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Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with N-METHYL-FHBT Descriptor: 6-[(2R)-2-(fluoromethyl)-3-hydroxy-propyl]-1,5-dimethyl-pyrimidine-2,4-dione, SULFATE ION, Thymidine kinase Authors: Pernot, L, Perozzo, R, Westermaier, Y, Martic, M, Ametamey, S, Scapozza, L. Deposit date: 2011-04-01 Release date: 2011-08-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo. Nucleosides Nucleotides Nucleic Acids, 30, 2011
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2011-04-01
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