Supplementary Table 1 and Supplementary Methods Table 1
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<strong>Supplementary Table 1</strong>: Clinicopathological features, TERT-related molecular data and telomere lengths of analyzed thyroid tumor series expressed in a.u.f. (arbitrary units of fluorescence). Na: not available data. <br> <strong>Supplementary methods table 1</strong>: Log2CPMs (log2 counts per million) normalized gene expression matrix of 26 genes involved in telomere maintenance (rows) for the 106 tumor series (columns). Tumor/gene expression cells of <em>TERT </em>probes with more than 3 normalized reads are colored in pink. The TERT_AVG<em> </em>row corresponds to the mean expression values of the 4 <em>TERT </em>probes for each tumor. Tumor cells with at least 1 probe with more than 3 reads are colored in pink and these were considered positive for <em>TERT </em>expression in subsequent analyses. Outlier gene expression thresholds used to generate the gene expression print in Figure 1B (<em>TERC</em>, <em>TCAB1</em>, <em>DKC1</em>, <em>NAT10</em>, <em>TINF2 </em>and <em>POT1</em>) are indicated. Two-tailed Mann-Whitney U-test p-value and FDR-adjusted p-value for the differential gene expression analysis between tumors classes (DF and PP) are included (colums DF and DG, respectively). DF: tumors from disease-free patients; PP: clinically aggressive tumors (PP, n=48).
提供机构:
Guadalix, Sonsoles; Letón, Rocío; Torres-Pérez, Rafael; Monteagudo, María; Ruiz-Llorente, Sergio; Moya, Francisco J.; Pita, Guillermo; Gonzalez-Neira, Anna; Currás-Freixes, Maria; Leandro-García, Luis Javier; Rodríguez-Perales, Sandra; Jordà, Mireia; Riesco-Eizaguirre, Garcilaso; Montero-Conde, Cristina; Rodriguez-Antona, Cristina; Megías, Diego; Martínez, Paula; Zafon, Carles; Martínez-Puente, Natalia; Martínez-Montes, Ángel M.; Robledo, Mercedes; Cascón, Alberto; Pérez-Martínez, Manuel; González-García, Patricia; Caleiras, Eduardo; Galofré, Juan Carlos; García-Tobar, Laura; Mancikova, Veronika; Blasco, Maria A.; Gil, Eduardo
创建时间:
2022-08-24



