Prophage-encoded methyltransferase upregulates virulence to drive adaptation in an outbreak of community-acquired methicillin-resistant Staphylococcus aureus. Prophage-encoded methyltransferase upregulates virulence to drive adaptation in an outbreak of community-acquired methicillin-resistant Staphylococcus aureus

To determine the effects of phage adenine methyltransferase (pamA) on gene expression in WT USA300 (LAC*) Overall design: Comparative gene expression analysis of WT::pamA (USA300 LAC* containing a single copy of constituatively expressed pamA) and WT::EV control.