Energetic portrait of the amyloid beta transition state
收藏Alliance of Genome Resources2026-08-01 收录
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In this study we use massively parallel combinatorial mutagenesis, a kinetic selection assay, and machine learning to better understand the nucleation reaction of amyloid beta (Aꞵ42), the protein that aggregates as a hallmark of Alzheimer’s disease (AD) and is mutated to cause familial AD.
