Transcriptome analysis of EGR1 knock-down eutopic endometrial mesenchymal stem cells by RNA-sequencing in patients with adenomyosis.

To identify differentially expressed genes (DEGs) and molecular pathways in EGR1 knock-down endometrial mesenchymal stem cells (eMSCs) from adenomyosis patients and provide a new insight into disease mechanisms at transcriptome level. Overall design: Gene expression profiling of EGR1 knock-down endometrial mesenchymal stem cells (EGR1-KD) and scrambled-sequence control (Scr) were analyzed by using RNA-sequencing.