Individualized and effects of FOS and GOS on human glucose level on OGTT and gut microbiome. Individualized response of OGTT and microbiome to prebiotic intervention

A randomized double-blind self-controlled cross-over study was performed with 35 adults (18 healthy, 17 overweight) treated daily with FOS and GOS for 9 days (16 g/day). Faeces sampling, OGTT and impedancemetry were performed before and after intervention. The gut microbial composition was profiled via surveys of 16S rRNA-encoding gene sequence from Ion Torrent platform and bioinformatics using QIIME.