Human in-vitro differentiated IgE+ and IgG+ Germinal Centre B cells, plasma blasts and plasma cells were isolated by flow cytometry and subjected to transcriptome analysis using the Illumina HumanHT-1

NIAID Data Ecosystem40

Characteristics of the study population.

临床免疫学

CD4+ T细胞分析

#23 subjects’ blood samples were unavailable for testing CD4+T cell counts. Characteristics of the study population.

NIAID Data Ecosystem30

Effect of allergen sensitization on gene expression in dendritic cells from neonates of asthmatic vs control mothers. Mus musculus

哮喘病理机制

过敏免疫应答

This study aims to demonstrate the link between epigenome-wide methylation aberrations at birth and genomic transcriptional changes upon allergen sensitization that occur in the neonatal dendritic cel

NIAID Data Ecosystem40

Single-cell transcriptomic analysis of mouse lung CD11b+ dendritic cells post allergic sensitization

单细胞转录组学

过敏免疫应答

Conventional dendritic cells (cDCs) in the lung that drive effector T cell differentiation, and initiate allergic responses upon inhalation of allergens. However, since CD11b+ cDCs are heterogeneous,

NIAID Data Ecosystem40

Allergen challenged CD4+ cells from allergic patients and healthy controls

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